PROMOGRAN PRISMA Rope Dressing

How it Works

Cellulose is a major component of all plants.  Once oxidized, ORC (Oxidized Regenerated Cellulose) is completely bioresorbable, and readily degrades through fluid absorption and subsequent gelling.

Studies show ORC:

• Has hemostatic properties
• Stimulated cell migration and growth
• Has bactericidal properties
• Reduced protease activity levels, specifically elastase and MMPs
• Scavenged free radicals and bound excess metal ions

Collagen is essential for new tissue generation. This family of structural proteins attracts cells to the wound area and forms the underlying layer of cell adhesion that induces cell growth and helps build new proteins. 

There are four main phases:

1.  Hemostasis – blood vessels constrict and platelets stick together to seal the break in the blood vessel wall. Coagulation occurs to reinforce the platelet plug with fibrin, serving as a molecular binding agent.
2. Inflamation – white blood cells, growth factors, nutrients, and enzymes create swelling, heat, pain, and redness. The wound is at risk for stalling, leading to delayed wound healing.
3. Proliferative Phase – new tissues are built and blood vessels are constructed. Epithelial cells resurface the injury, which happens faster when wounds are kept moist and hydrated.
4. Maturation/Remodeling – collegan is remodeled and the wound fully closes. Cross-linking of collagen reduces scar thickness and makes the skin of the wound stronger.